In brief

Our research aims at identifying the neuronal circuits that execute movements and support their adaptive nature. We principally study breathing and locomotion, two vital behaviors that are largely conserved across species. Our current research projects aim at unveiling how breathing and locomotion are dynamically modulated according to internal or external needs, such as transition from rest to exercise, changes in posture or locomotor direction. These questions are addressed by a multidisciplinary strategy combining state-of-the-art viral-based anatomical tracings on dedicated transgenic mouse lines, neuro-anatomy, and functional investigations using electrophysiology, optogenetic and behavioral analysis.