Jobs

General information
• Reference : UMR9197-ODILEC2-077
• Workplace : GIF SUR YVETTE
• Date of publication : Tuesday, November 03, 2020
• Type of Contract : FTC Scientist
• Contract Period : 12 months
• Expected date of employment : 1 February 2021
• Proportion of work : Full time
• Remuneration : between € 2,666 and € 3,833 gross monthly depending on experience
• Desired level of education : Higher than 5-year university degree
• Experience required : 1 to 4 years

Missions
The hired individual (postdoctoral researcher) will contribute to research projects supported by an Equipe FRM grant entitled « Neurogenetics of the blind cavefish, Astyanax mexicanus ».

Activities
Research: morphogenetic mechanisms underlying eye malformations in the blind Mexican cavefish.

Skills
• Theoretical: development biology, neurobiology, evo-devo.
• Technical: genome edition, transgenesis in fish models; imaging; embryology.
• Motivation, rigor, inventiveness, precision.
• Ability to work in a team and in autonomy.

Work Context
The hired individual will work at the Paris-Saclay Institute of Neuroscience (Neuro-PSI), which currently gathers about 25 research teams (~300 people). She/He will join the team “Development and evolution of the forebrain” (2 CNRS researchers, 1 associate professor, 1 engineer, 1 technician, 1 postdoc, 2 PhD students), and will work under the supervision of the team leader (S. Rétaux).

Contact
Sylvie Rétaux

General information
• Reference : UMR9197-ALIGIN-017
• Workplace : GIF-SUR-YVETTE
• Date of publication : Friday, November 20, 2020
• Type of Contract : FTC Scientist
• Contract Period : 24 months
• Expected date of employment : 1 January 2021
• Proportion of work : Full time
• Remuneration : 3 920 – 5 580 gross monthly depending on experience
• Desired level of education : PhD
• Experience required : Indifferent

Missions
The « Computational Neuroscience » group of NeuroPSI Institute and the European Institute for Theoretical Neuroscience (EITN), recruit a postdoctoral researcher for the computer modeling of neural networks implicated in decision making, in collaboration with Ruben Moreno-Bote (Barcelona). This work will contribute to the European-funded projects « COREDEM » and « Human Brain Project ».

Activities
• Computer based modeling and analysis
• Adaptation of existing neural models to include decision making
• Participate to the scientific animation of the group and the EITN

Skills
• Excellent knowledge of neuroscience and computational neuroscience
• Knowledge of biophysics
• Programming
• Excellent knowledge of English language
• Being autonomous but also work in a team

Work Context
The « Computational Neuroscience » group is composed of 10 researchers and 3 engineers, and is part of the « Integrative and Computational Neuroscience » (ICN) department of the Paris-Saclay Neuroscience Institute (NeuroPSI). These groups also run the European Institute of Theoretical Neuroscience (EITN). The research team is inter-disciplinary, at the interface between physics, computer science and neurosciences, with a strong implication in European projects. The applicant will work under the supervision of the team leader Alain Destexhe.

Contact
Alain Destexhe

General information
• Reference : UMR9197-ODILEC2-078
• Workplace : ORSAY
• Date of publication : Tuesday, November 17, 2020
• Type of Contract : FTC Scientist
• Contract Period : 6 months
• Expected date of employment : 1 January 2021
• Proportion of work : Full time
• Remuneration : gross monthly salary approximately € 2,729
• Desired level of education : 5-year university degree
• Experience required : 1 to 4 years

Missions
The Duchenne muscular dystrophy (DMD) syndrome is associated with variable degrees of cognitive impairments that may include intellectual disability and neuropsychiatric disorders. The main objective will be to better understand how distinct mutations within the same gene (DMD gene) responsible for this neuromuscular disease influence the severity and/or nature of the comorbid cognitive and behavioral disturbances. The study shall lead to the identification of phenotypes that can serve as a marker of the efficacy of treatments for preclinical studies.

Activities
The applicant will organize and undertake in-depth comparative studies of several mouse models holding distinct mutations in the DMD gene to address a range of cognitive and executive functions in a variety of behavioral paradigms. He/she will also perform statistical analyses, generate and archive results reports, and contribute to dissemination of the produced knowledge through scientific written and oral communications in French and/or English.

Skills
The applicants should have a recent PhD in neuroscience and experience in mouse behavior and biostatistics; hands-on experience in intra-cranial surgeries will be a plus. The applicant is expected to have good verbal/written communication skills in English and a critical approach to scientific literature.

Work Context
The applicant will independently carry out his/her project under the direction of C Vaillend, in interaction with other researchers, students and technicians, in a collaborative environment including molecular and clinical studies, at the international level as part of a project funded by the European Union (European Union’s Horizon 2020 research and innovation program).

Additional Information
The contract may be extended.

Contact
Cyrille Vaillend

General information
• Reference : UMR9197-ODILEC2-078
• Reference : UMR9197-ANDDAV-007
• Workplace : GIF SUR YVETTE
• Date of publication : Thursday, June 24, 2021
• Type of Contract : FTC Scientist
• Contract Period : 18 months
• Expected date of employment : 1 September 2021
• Proportion of work : Full time
• Remuneration : between 2728 and 4323 € gross per month, depending on experience
• Desired level of education : PhD
• Experience required : Indifferent

Missions
A position in neuronal network modelling and simulation is available within the Neuroinformatics research group of the Paris-Saclay Institute of Neuroscience, as part of the Human Brain Project.
The large number of different simulation environments in neuroscience presents both a problem and an opportunity. Since each simulator has its own programming interface and output data format, reproducing, reusing, or combining models written for different simulators typically presents considerable difficulty. On the other hand, since each simulation environment has a different balance between efficiency, flexibility, scalability and user-friendliness, we can choose the most appropriate one for a given problem, or cross-check the results obtained with different tools.
Simulator-agnostic model representation languages such as NeuroML and PyNN allow us to preserve the advantages of simulator diversity while reducing or eliminating the disadvantages, thereby making reproducibility and reuse much easier. Such languages let us take a single model description and simulate it in different environments without having to reimplement the model each time.
The aim of this project is to expand the scope of PyNN from networks of simplified neuron models, such as integrate-and-fire, to networks consisting of biophysically- and morphologically-detailed neuron models, targeting the NEURON and Arbor simulators, the SpiNNaker and BrainScaleS neuromorphic computing systems, and interoperability with NeuroML and the SONATA format.

Activities
• Extend the PyNN API to multicompartmental neuron models, incorporating biophysical models of ion channels, synaptic mechanisms and intracellular calcium dynamics, building on existing prototypes and in consultation with the wider modelling community
• complete the implementation of this API for the NEURON and Arbor simulators
• develop input/output support for the NeuroML and SONATA formats
• develop appropriate unit and system tests
• write documentation and tutorials, and participate in user training activities
• publish on topics of modelling/simulation technologies, workflows and model sharing/reuse

Skills
• PhD in neuroscience, physics, computer science, or a closely related discipline
• preferably with experience of computational modelling.
• experience of simulation tools often used in computational neuroscience, such as NEURON, NEST or Brian
• knowledge of computer programming (in Python, C++, MATLAB or other)
• knowledge of French would be helpful but is not required, as English is the working language of the project.

Work Context
The Paris-Saclay Institute of Neuroscience is a research unit of the CNRS and the University Paris-Saclay, located in Gif sur Yvette, about 40 minutes from central Paris. The Neuroinformatics research group develops novel informatics tools and approaches for neuroscience data sharing, modelling and simulation, and for brain-inspired computing. This post is funded by the Human Brain Project, an EU Flagship initiative in which over 100 partners work together to build a completely new information computing technology infrastructure for neuroscience and for brain-related research in medicine and computing.

Contact
Andrew Davison

General information
• Reference : UMR9197-ALIGIN-020
• Workplace : GIF SUR YVETTE
• Date of publication : Monday, June 14, 2021
• Type of Contract : FTC Technical / Administrative
• Contract Period : 18 months
• Expected date of employment : 1 September 2021
• Proportion of work : Full time
• Remuneration : between 2139 and 2727 € gross per month, depending on experience
• Desired level of education : 3-year university degree
• Experience required : Indifferent

Missions
The Neuroinformatics research group of the Paris-Saclay Institute of Neuroscience develops a number of web services and applications for neuroscience data sharing, modelling and simulation, and for brain-inspired computing, as part of the EBRAINS research infrastructure (https://ebrains.eu) developed by the Human Brain Project. We wish to recruit a DevOps engineer to participate in the development, documentation, quality control, and deployment of these web services and applications.

Activities
• Development, testing and deployment of scientific web services and browser-based applications (backend Python, frontend HTML/Javascript/CSS)
• automation of service deployment
• implementation of centralised logging and monitoring

Skills
Architecture et l’environnement technique du système d’information
• Good knowledge of Python and/or Javascript/CSS (ReactJS, Angular)
• configuration of web servers (nginx), reverse proxies, load balancing, monitoring
• cloud computing, Docker
• continuous integration and deployment technologies

Work Context
The Paris-Saclay Institute of Neuroscience is a research unit of the CNRS and the University Paris-Saclay, located in Gif sur Yvette, about 40 minutes from central Paris. The Neuroinformatics research group (https://neuropsi.cnrs.fr/en/departments/icn/group-leader-andrew-davison/) develops novel informatics tools and approaches for neuroscience data sharing, modelling and simulation, and for brain-inspired computing. This post is funded by the Human Brain Project, an EU Flagship initiative in which over 100 partners work together to build a completely new information computing technology infrastructure for neuroscience and for brain-related research in medicine and computing.

Contact
Aline GINOIS

Informations générales
• Référence : UMR9197-ODILEC2-086
• Lieu de travail : GIF SUR YVETTE puis SACLAY
• Date de publication : lundi 5 juillet 2021
• Type de contrat : CDD Technique/Administratif
• Durée du contrat : 6 mois
• Date d’embauche prévue : 1 septembre 2021
• Quotité de travail : Temps complet
• Rémunération : salaire brut mensuel entre 1988 € et 2123 € selon expérience (selon la grille salariale du CNRS)
• Niveau d’études souhaité : Bac+2
• Expérience souhaitée : Indifférent

Missions
Installer et administrer les ressources nécessaires à la gestion du parc informatique matériel et logiciel (Windows et Mac)
Assister les utilisateurs dans la mise en œuvre et l’exploitation de leur environnement informatique, et ce dans le contexte de l’installation du laboratoire dans un nouveau bâtiment à partir de septembre 2021.

Activités
• Gérer, maintenir et faire évoluer le parc matériel et logiciel
• Suivre quotidiennement l’exploitation
• Participer à l’installation et la mise à jour des postes de travail, en accord avec la politique informatique de NeuroPSI
• Participer à l’installation et la gestion de la téléphonie ToIP.
• Conseiller, accompagner et former les utilisateurs
• Assurer le support technique des utilisateurs
• Participer à la mise en place du Système d’Information de NeuroPSI dans le nouveau bâtiment à Saclay.
• Rédiger la documentation fonctionnelle et technique.

Compétences Principales :
• Architecture et l’environnement technique du système d’information
• Techniques de virtualisation (connaissance générale)
• Diagnostic et résolution de problèmes
• Méthodes de mise en production
• Connaissance de la réglementation en matière de protection des données personnelles et de sécurité informatique
• Accompagner la conduite du changement
• Anglais technique (connaissance générale)

Compétences opérationnelles :
• Établir un diagnostic (maîtrise)
• Gérer les situations d’urgence
• Rédiger et mettre à jour la documentation fonctionnelle et technique
• Gérer la sécurité de l’information

Compétences comportementales :
• Bonne aptitude au travail en équipe
• Rigueur et implication professionnelle
• Capacité à transmettre ses connaissances à des publics variés

Contexte de travail
L’Institut des Neurosciences Paris Saclay (NeuroPSI) actuellement sur deux sites géographiques (Orsay et Gif-sur-Yvette) regroupera dans un nouveau bâtiment sur le campus du CEA Saclay une masse critique d’équipes de haut niveau (septembre 2021) qui par la réunion synergique de leurs champs d’investigation porteront l’ambition de répondre aux grands enjeux des neurosciences contemporaines.
Le service informatique de l’Institut (4-5 personnes) met en place une architecture de nouveaux équipements dans un bâtiment neuf. Il aura pour mission de gérer l’ensemble des systèmes d’information et des services associés nécessaires au support informatique de l’activité de recherche (équipes de recherche, plateaux techniques, administration et services communs – environ 250 personnes) en liaison avec l’environnement local (CEA, CNRS et Université-Paris-Saclay), national et international.

Contact
Odile LECQUYER