The team « NeuroInfection and Immunity » studies central nervous system infections, which are often lethal or cause severe neurological deficits in newborns. The host inflammatory response attacks microbes, but may also be highly deleterious to the brain. We use transparent zebrafish larva to visualize virus infected cells in real-time by microscopy, as well as the immune response simultaneously. We analyze the consequences of viral encephalitis as well as the impact of inflammation itself on the nervous system development.
The team, which is doubly affiliated to CNRS and Institut Pasteur, established itself in 2021 in the new Saclay building.