Group leader: François Rouyer

Molecular Genetics of Circadian Rhythms

In brief

Our research aims at understanding how the brain controls sleep-wake rhythms. Sleep-wake rhythms are controlled by a brain circadian clock that is synchronized with day-night cycles by environmental cues, such as light and temperature. We use neurogenetics approaches in Drosophila to understand how a multi-oscillators brain clock is organized at the molecular and cellular levels as well as at the scale of neuronal networks, how the brain translates circadian information into sleep-wake rhythms, and how sensory signals are integrated to entrain the clock neuronal network and adapt the behavior to the environment.