Xiao-Jing Wang

Xiao-Jing Wang

Computational Laboratroy of Cortical dynamics New York University, USA

Distributed dynamics and cognition in the multiregional neocortex.

Abstract: With technological advances in neuroanatomy and neurophysiology, neuroscience of multi-regional brain-wide neural circuits is taking off. However, recent studies have renewed the debate on local versus global neural information encoding and processing. Here, I will propose a mechanism for functional specificity in a cortex made of repeated canonical local circuits à la Kevan Martin and Rodney Douglas. I will introduce large-scale modeling of cortex based on connectomic data for monkeys and mice, and highlight macroscopic gradients of synaptic excitation and inhibition as a general principle of the large-scale cortical organization. Then, I will discuss findings about a hierarchy of timescales, distributed working memory and simple decision-making. This line of work suggests that the new concept of “bifurcation in space” can explain functional modularity compatible with distributed neural representations in the neocortex.

Invité par Alain Destexhe

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Date

Juin 18 2024

Heure

11h00
Catégorie

Organisateur

DESTEXHE Alain
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