Thierry Bal Team

Homeostasis, Perception and States (HOPES)
Our research

Latest in vitro results

• We proposed a mechanism for selective attention in thalamic neurons using a neuron-machine interface (dynamic-clamp). (Behuret et al., Frontiers in Neural Circuits, 2015; Behuret et al., PLoS Comput. Biol., 2013, collaboration with Y. Frégnac).

• First demonstration in vertebrate of synaptic homeostasis of the neuromuscular transmission (Ouanounou et al., eLife, 2016).

• Magnetrodes: First demonstration of magnetic field recording in biological cells using the Giant Magneto Resistance effect (GMR). Collaboration with the CEA. (Barbieri et al., Scientific Report, 2016).

• We tested the theory that extracellular medium around neurons has non-ohmic properties (which may impact on the understanding of extracellular recordings such as EEG or LFP). (Gomes et al., Biophys. J., 2016, collaboration with A. Destexhe).



• We used voltage sensitive dye imaging (VSD) to probe dendritic and axonal activities in neurons, and we installed the technique in NeuroPSI. (Casale et al;, J. Neuroscience, 2015)

Latest in vivo results

• We propose that long-range horizontal synaptic connections in the primary visual cortex constitute the neural correlate of a perceptual bias in speed detection. (Gerard-Mercier et al. , J. Neuroscience, 2016)

• We demonstrate the hidden complexity behind the Simple or Complex nature of receptive fields in the primary visual cortex that relies on the imbalance between the weights of the Simple-like and Complex-like synaptic contributions. (Fournier et al., J. Neuroscience, 2014)

• The functional properties of the primary visual cortex network, as measured from the receptive field estimates, are not fixed, but instead adapt to the statistical properties of the visual input. (Fournier et al., Nature Neuroscience, 2011)