Our work is based on electrophysiological recordings in the thalamo-cortical auditory system. We first demonstrated that the receptive fields of thalamo-cortical neurons are selectively modified after a brief session of aversive conditioning. Then we studied the influence of Acetylcholine and Norepinephrine on the receptive fields of auditory cortex neurons. After investigating the role of tone-evoked oscillations and of bursts in the thalamo-cortical system, we spent the recent years studying the neural code underlying the discrimination of communication sounds.
> Cazala A. Giret N, Edeline J-M & Del Negro C. (2019) Neuronal encoding in a high level auditory area: from sequential order of elements to grammatical structure, J. Neuroscience. 39(31) 6150-6161.
> Adenis V, Gourévitch B, Mamelle E, Recugnat M, Stahl P, Gnansia D, Nguyen Y, Edeline JM. (2018) ECAP growth function to increasing pulse amplitude or pulse duration demonstrates large inter-animal variability that is reflected in auditory cortex of the guinea pig. PLoS One.13(8) e0201771
Team leaders
Catherine DEL NEGRO, Assistant Professor Paris-Saclay University, Neural Code & Auditory Perception, Code neuronal & perception auditive
Jean-Marc EDELINE, Senior Research Scientist, Neural Code & Auditory Perception, Code neuronal & perception auditive
Members
José-Manuel CANCELA, Research Scientist, Neural Code & Auditory Perception, Code neuronal & perception auditive
Nicolas GIRET, Research Scientist, Neural Code & Auditory Perception, Code neuronal & perception auditive