Article dans une revue

2022

ref_biblio

Alice del Giovane, Mariagiovanna Russo, Linda Tirou, Hélène Faure, Martial Ruat, et al.. Smoothened/AMP-Activated Protein Kinase Signaling in Oligodendroglial Cell Maturation. Frontiers in Cellular Neuroscience, 2022, 15, pp.801704. ⟨10.3389/fncel.2021.801704⟩. ⟨hal-04197782⟩

Accès au texte intégral et bibtex

2021

ref_biblio

Linda Tirou, Mariagiovanna Russo, Helene Faure, Giuliana Pellegrino, Clement Demongin, et al.. Sonic Hedgehog receptor Patched deficiency in astrocytes enhances glucose metabolism in mice. Molecular metabolism, 2021, 47, pp.101172. ⟨10.1016/j.molmet.2021.101172⟩. ⟨hal-03195885⟩

Accès au texte intégral et bibtex

2020

ref_biblio

Linda Tirou, Mariagiovanna Russo, Hélène Faure, Giuliana Pellegrino, Ariane Sharif, et al.. C9C5 positive mature oligodendrocytes are a source of Sonic Hedgehog in the mouse brain. PLoS ONE, 2020, 15 (2), pp.e0229362. ⟨10.1371/journal.pone.0229362⟩. ⟨inserm-02492142⟩

Accès au texte intégral et bibtex

2019

ref_biblio

Chia-Hsiang Chang, Marco Zanini, Hamasseh Shirvani, Jia-Shing Chen, Hua Yu, et al.. Atoh1 Controls Primary Cilia Formation to Allow for SHH-Triggered Granule Neuron Progenitor Proliferation. Developmental Cell, 2019, 48 (2), pp.184-199.e5. ⟨10.1016/j.devcel.2018.12.017⟩. ⟨hal-02020341⟩

Accès au bibtex

2018

ref_biblio

Alexandra Chicheportiche, Martial Ruat, François D Boussin, Mathieu Daynac. Isolation of Neural Stem and Progenitor Cells from the Adult Brain and Live Imaging of Their Cell Cycle with the FUCCI System.. Methods in Molecular Biology, 2018, Cellular Quiescence, 1686, pp.69-78. ⟨10.1007/978-1-4939-7371-2_5⟩. ⟨hal-01661733⟩

Accès au bibtex

2016

ref_biblio

Alessandra Chiarenza, Fabrizio Manetti, Elena Petricci, Martial Ruat, Antonella Naldini, et al.. Novel Acylguanidine Derivatives Targeting Smoothened Induce Antiproliferative and Pro-Apoptotic Effects in Chronic Myeloid Leukemia Cells.. PLoS ONE, 2016, 11 (3), pp.e0149919. ⟨10.1371/journal.pone.0149919⟩. ⟨hal-01366756⟩

Accès au bibtex

ref_biblio

Mathieu Daynac, Linda Tirou, Hélène Faure, Marc-André Mouthon, Laurent R Gauthier, et al.. Hedgehog Controls Quiescence and Activation of Neural Stem Cells in the Adult Ventricular-Subventricular Zone.. Stem Cell Reports, 2016, 7 (4), pp.735-748. ⟨10.1016/j.stemcr.2016.08.016⟩. ⟨hal-01373136⟩

Accès au bibtex

ref_biblio

Audrey Fleury, Lucile Hoch, M Carmen Martinez, Hélène Faure, Maurizio Taddei, et al.. Hedgehog associated to microparticles inhibits adipocyte differentiation via a non-canonical pathway.. Scientific Reports, 2016, 6, pp.23479. ⟨10.1038/srep23479⟩. ⟨hal-01304661⟩

Accès au bibtex

ref_biblio

Lionel Kiefer, Floriane Beaumard, Tatiana Gorojankina, Hélène Faure, Martial Ruat, et al.. Design and synthesis of calindol derivatives as potent and selective calcium sensing receptor agonists.. Bioorganic and Medicinal Chemistry, 2016, 24 (4), pp.554-69. ⟨10.1016/j.bmc.2015.12.019⟩. ⟨hal-01366761⟩

Accès au bibtex

ref_biblio

Fabrizio Manetti, Elena Petricci, Annalisa Gabrielli, Andrè Mann, Hélène Faure, et al.. Design, synthesis and biological characterization of a new class of osteogenic (1H)-quinolone derivatives. European Journal of Medicinal Chemistry, 2016, 121, pp.747-57. ⟨10.1016/j.ejmech.2016.05.062⟩. ⟨hal-01366729⟩

Accès au bibtex

2015

ref_biblio

Mathieu Daynac, Lise Morizur, Thierry Kortulewski, Laurent R Gauthier, Martial Ruat, et al.. Cell Sorting of Neural Stem and Progenitor Cells from the Adult Mouse Subventricular Zone and Live-imaging of their Cell Cycle Dynamics.. Journal of visualized experiments : JoVE, 2015, 103, ⟨10.3791/53247⟩. ⟨hal-01240874⟩

Accès au bibtex

ref_biblio

Yannick Gache, Florence Brellier, Sophie Rouanet, Sahar Al-Qaraghuli, Maria Goncalves-Maia, et al.. Basal Cell Carcinoma in Gorlin’s Patients: a Matter of Fibroblasts-Led Protumoral Microenvironment?. PLoS ONE, 2015, 10 (12), pp.e0145369. ⟨10.1371/journal.pone.0145369⟩. ⟨hal-01257867⟩

Accès au texte intégral et bibtex

ref_biblio

Lucile Hoch, Hélène Faure, Hermine Roudaut, Angele Schoenfelder, André Mann, et al.. MRT-92 inhibits Hedgehog signaling by blocking overlapping binding sites in the transmembrane domain of the Smoothened receptor.. FASEB Journal, 2015, 29 (5), pp.1817-1829 ⟨10.1096/fj.14-267849⟩. ⟨hal-01142537⟩

Accès au bibtex

2014

ref_biblio

Julien Ferent, Martial Ruat, Elisabeth Traiffort. [Symmetric or asymmetric division: sonic Hedgehog controls the fate of neural stem cells].. Médecine/Sciences, 2014, 30 (6-7), pp.705-8. ⟨10.1051/medsci/20143006026⟩. ⟨hal-01055290⟩

Accès au bibtex

ref_biblio

Julien Ferent, Loïc Cochard, Hélène Faure, Maurizio Taddei, Heidi Hahn, et al.. Genetic activation of Hedgehog signaling unbalances the rate of neural stem cell renewal by increasing symmetric divisions.. Stem Cell Reports, 2014, 3 (2), pp.312-23. ⟨10.1016/j.stemcr.2014.05.016⟩. ⟨hal-01142521⟩

Accès au bibtex

ref_biblio

Martial Ruat, Lucile Hoch, Hélène Faure, Didier Rognan. Targeting of Smoothened for therapeutic gain.. Trends in Pharmacological Sciences, 2014, 35 (5), pp.237-46. ⟨10.1016/j.tips.2014.03.002⟩. ⟨hal-01055292⟩

Accès au bibtex

2013

ref_biblio

Julien Ferent, Martial Ruat, Elisabeth Traiffort. Investigation of the proteolipid protein promoter activity during demyelination and repair.. Differentiation, 2013, 85 (4-5), pp.182-9. ⟨10.1016/j.diff.2013.05.002⟩. ⟨hal-00851056⟩

Accès au bibtex

ref_biblio

Julien Ferent, Céline Zimmer, Pascale Durbec, Martial Ruat, Elisabeth Traiffort. Sonic Hedgehog signaling is a positive oligodendrocyte regulator during demyelination.. Journal of Neuroscience, 2013, 33 (5), pp.1759-72. ⟨10.1523/JNEUROSCI.3334-12.2013⟩. ⟨hal-00843376⟩

Accès au bibtex

ref_biblio

Tatiana Gorojankina, Lucile Hoch, Hélène Faure, Hermine Roudaut, Elisabeth Traiffort, et al.. Discovery, molecular and pharmacological characterization of GSA-10, a novel small-molecule positive modulator of Smoothened.. Molecular Pharmacology, 2013, 83 (5), pp.1020-9. ⟨10.1124/mol.112.084590⟩. ⟨hal-00851060⟩

Accès au bibtex

ref_biblio

Marie-Ange Renault, Fanny Robbesyn, Candice Chapouly, Qinyu Yao, Soizic Vandierdonck, et al.. Hedgehog-dependent regulation of angiogenesis and myogenesis is impaired in aged mice.. Arteriosclerosis, Thrombosis, and Vascular Biology, 2013, 33 (12), pp.2858-66. ⟨10.1161/ATVBAHA.113.302494⟩. ⟨hal-00919989⟩

Accès au bibtex

ref_biblio

Marie-Ange Renault, Candice Chapouly, Qinyu Yao, Frédéric Larrieu-Lahargue, Soizic Vandierdonck, et al.. Desert hedgehog promotes ischemia-induced angiogenesis by ensuring peripheral nerve survival.. Circulation Research, 2013, 112 (5), pp.762-70. ⟨10.1161/CIRCRESAHA.113.300871⟩. ⟨hal-00800262⟩

Accès au bibtex

ref_biblio

Martial Ruat, Elisabeth Traiffort. Roles of the calcium sensing receptor in the central nervous system.. Best Practice and Research: Clinical Endocrinology and Metabolism, 2013, 27 (3), pp.429-42. ⟨10.1016/j.beem.2013.03.001⟩. ⟨hal-00851054⟩

Accès au bibtex

ref_biblio

Martial Ruat, Lucile Hoch, Hélène Faure, Didier Rognan. [Structure of the Smoothened receptor].. Médecine/Sciences, 2013, 29 (10), pp.855-60. ⟨10.1051/medsci/20132910012⟩. ⟨hal-00919986⟩

Accès au bibtex

ref_biblio

Elisabeth Traiffort, Seana O'Regan, Martial Ruat. The choline transporter-like family SLC44: properties and roles in human diseases.. Molecular Aspects of Medicine, 2013, 34 (2-3), pp.646-54. ⟨10.1016/j.mam.2012.10.011⟩. ⟨hal-00851057⟩

Accès au bibtex

2012

ref_biblio

Angelika Horn, Katrin Palumbo, Cinzia Cordazzo, Clara Dees, Alfiya Akhmetshina, et al.. Hedgehog signaling controls fibroblast activation and tissue fibrosis in systemic sclerosis.. Arthritis and Rheumatism, 2012, epub ahead of print. ⟨10.1002/art.34444⟩. ⟨hal-00683585⟩

Accès au bibtex

ref_biblio

Angelika Horn, Trayana Kireva, Katrin Palumbo-Zerr, Clara Dees, Michal Tomcik, et al.. Inhibition of hedgehog signalling prevents experimental fibrosis and induces regression of established fibrosis.. Annals of the Rheumatic Diseases, 2012, epub ahead of print. ⟨10.1136/annrheumdis-2011-200883⟩. ⟨hal-00683578⟩

Accès au bibtex

ref_biblio

Alexandre Loupy, Suresh Krishna Ramakrishnan, Bharath Wootla, Régine Chambrey, Renaud de La Faille, et al.. PTH-independent regulation of blood calcium concentration by the calcium-sensing receptor. Journal of Clinical Investigation, 2012, 122 (9), pp.3355-3367. ⟨10.1172/JCI57407⟩. ⟨hal-03160918⟩

Accès au bibtex

ref_biblio

Alexandre Loupy, Suresh Krishna Ramakrishnan, Bharath Wootla, Régine Chambrey, Renaud de La Faille, et al.. PTH-independent regulation of blood calcium concentration by the calcium-sensing receptor.. Journal of Clinical Investigation, 2012, 122 (9), pp.3355-67. ⟨10.1172/JCI57407⟩. ⟨hal-00745053⟩

Accès au bibtex

ref_biblio

Martial Ruat, Hermine Roudaut, Julien Ferent, Elisabeth Traiffort. Hedgehog trafficking, cilia and brain functions.. Differentiation, 2012, 83 (2), pp.S97-104. ⟨10.1016/j.diff.2011.11.011⟩. ⟨hal-00683601⟩

Accès au texte intégral et bibtex

ref_biblio

Antonio Solinas, Hélène Faure, Hermine Roudaut, Elisabeth Traiffort, Angèle Schoenfelder, et al.. Acylthiourea, acylurea, and acylguanidine derivatives with potent hedgehog inhibiting activity.. Journal of Medicinal Chemistry, 2012, 55 (4), pp.1559-71. ⟨10.1021/jm2013369⟩. ⟨hal-00683600⟩

Accès au bibtex

2011

ref_biblio

Michel Bidet, Olivier R. Joubert, Benoit Lacombe, Marine Ciantar, Rony Nehmé, et al.. The hedgehog receptor patched is involved in cholesterol transport.. PLoS ONE, 2011, 6 (9), pp.e23834. ⟨10.1371/journal.pone.0023834⟩. ⟨hal-00637248⟩

Accès au texte intégral et bibtex

ref_biblio

Guillaume Guerlet, Thomas Spangenberg, André Mann, Hélène Faure, Martial Ruat. Synthesis and biological evaluation of desmethylveramiline, a micromolar Hedgehog inhibitor.. Bioorganic and Medicinal Chemistry Letters, 2011, 21 (12), pp.3608-12. ⟨10.1016/j.bmcl.2011.04.103⟩. ⟨hal-00637249⟩

Accès au bibtex

ref_biblio

Hermine Roudaut, Elisabeth Traiffort, Tatiana Gorojankina, Ludwig Vincent, Hélène Faure, et al.. Identification and mechanism of action of the acylguanidine MRT-83, a novel potent smoothened antagonist.. Molecular Pharmacology, 2011, 79 (3), pp.453-60. ⟨10.1124/mol.110.069708⟩. ⟨hal-00586202⟩

Accès au bibtex

ref_biblio

Martial Ruat, Elodie Angot, Elisabeth Traiffort. [Shh signal and its functional roles in normal and diseased brain].. Médecine/Sciences, 2011, 27 (11), pp.979-85. ⟨10.1051/medsci/20112711014⟩. ⟨hal-00648875⟩

Accès au bibtex

ref_biblio

Wei Xiong, Tao Liu, Yeshi Wang, Xaiowei Chen, Lei Sun, et al.. Extracellular Ca2+ Directly Inhibits Exocytosis in Neurons. Biophysical Journal, 2011, 100 (3), pp.185a - 186a. ⟨10.1016/j.bpj.2010.12.1232⟩. ⟨hal-01710262⟩

Accès au bibtex

ref_biblio

Wei Xiong, Tao Liu, Yeshi Wang, Xiaowei Chen, Lei Sun, et al.. An inhibitory effect of extracellular ca on ca-dependent exocytosis.. PLoS ONE, 2011, 6 (10), pp.e24573. ⟨10.1371/journal.pone.0024573⟩. ⟨hal-00637244⟩

Accès au bibtex

2010

ref_biblio

Wenyan Chen, Jeremy B Bergsman, Xiaohua Wang, Gawain Gilkey, Carol-Renée Pierpoint, et al.. Presynaptic external calcium signaling involves the calcium-sensing receptor in neocortical nerve terminals.. PLoS ONE, 2010, 5 (1), pp.e8563. ⟨10.1371/journal.pone.0008563⟩. ⟨hal-00449394⟩

Accès au bibtex

ref_biblio

Lionel Kiefer, Tatiana Gorojankina, Philippe Dauban, Hélène Faure, Martial Ruat, et al.. Design and synthesis of cyclic sulfonamides and sulfamates as new calcium sensing receptor agonists.. Bioorganic and Medicinal Chemistry Letters, 2010, 20 (24), pp.7483-7487. ⟨10.1016/j.bmcl.2010.10.006⟩. ⟨hal-00537890⟩

Accès au bibtex

ref_biblio

Fabrizio Manetti, Hélène Faure, Hermine Roudaut, Tatiana Gorojankina, Elisabeth Traiffort, et al.. Virtual screening-based discovery and mechanistic characterization of the acylthiourea MRT-10 family as Smoothened antagonists.. Molecular Pharmacology, 2010, epub ahead of print. ⟨10.1124/mol.110.065102⟩. ⟨hal-00506994⟩

Accès au bibtex

ref_biblio

Elisabeth Traiffort, Elodie Angot, Martial Ruat. Sonic Hedgehog signaling in the mammalian brain.. Journal of Neurochemistry, 2010, 113 (3), pp.576-90. ⟨10.1111/j.1471-4159.2010.06642.x⟩. ⟨hal-00506983⟩

Accès au bibtex

2009

ref_biblio

Hélène Faure, Tatiana Gorojankina, Nadejda Rice, Philippe Dauban, Robert H. Dodd, et al.. Molecular determinants of non-competitive antagonist binding to the mouse GPRC6A receptor.. Cell Calcium, 2009, 46 (5-6), pp.323-32. ⟨10.1016/j.ceca.2009.09.004⟩. ⟨hal-00425461⟩

Accès au bibtex

ref_biblio

Olivia Fromigué, Eric Haÿ, Alain Barbara, Christophe Petrel, Elisabeth Traiffort, et al.. Calcium sensing receptor-dependent and -independent activation of osteoblast replication and survival by strontium ranelate.. Journal of Cellular and Molecular Medicine, 2009, 13 (8b), pp.2189-2199. ⟨10.1111/j.1582-4934.2008.00673.x⟩. ⟨hal-00385658⟩

Accès au bibtex

ref_biblio

Olivier R. Joubert, Rony Nehmé, Damien Fleury, Matthieu de Rivoyre, Michel Bidet, et al.. Functional studies of membrane-bound and purified human Hedgehog receptor Patched expressed in yeast.. Biochimica et Biophysica Acta - Molecular Cell Research, 2009, 1788 (9), pp.1813-21. ⟨10.1016/j.bbamem.2009.05.009⟩. ⟨hal-00408814⟩

Accès au bibtex

2008

ref_biblio

Elodie Angot, Karine Loulier, Kim T Nguyen-Ba-Charvet, Alain-Pierre Gadeau, Martial Ruat, et al.. Chemoattractive activity of sonic hedgehog in the adult subventricular zone modulates the number of neural precursors reaching the olfactory bulb.. Stem Cells / Stem Cells (Miamisburg), 2008, 26 (9), pp.2311-20. ⟨10.1634/stemcells.2008-0297⟩. ⟨hal-00334981⟩

Accès au bibtex

ref_biblio

Erika Harno, Gillian Edwards, Annie R. Geraghty, Donald T. Ward, Robert H. Dodd, et al.. Evidence for the presence of GPRC6A receptors in rat mesenteric arteries.. Cell Calcium, 2008, 44 (2), pp.210-9. ⟨10.1016/j.ceca.2007.11.011⟩. ⟨hal-00193489⟩

Accès au bibtex

ref_biblio

Arthur H. Weston, Mais Absi, Erika Harno, Annie R. Geraghty, Donald T. Ward, et al.. The expression and function of Ca(2+)-sensing receptors in rat mesenteric artery; comparative studies using a model of type II diabetes.. British Journal of Pharmacology, 2008, 154 (3), pp.652-62. ⟨10.1038/bjp.2008.108⟩. ⟨hal-00253729⟩

Accès au bibtex

2007

ref_biblio

Ludovic Collin, Sandrine Doretto, Monica Malerba, Martial Ruat, Emiliana Borrelli. Oligodendrocyte ablation affects the coordinated interaction between granule and Purkinje neurons during cerebellum development.. Experimental Cell Research, 2007, 313 (13), pp.2946-57. ⟨10.1016/j.yexcr.2007.05.003⟩. ⟨hal-00159967⟩

Accès au bibtex

ref_biblio

Christelle Masdeu, Véronique Bernard, Hélène Faure, Elisabeth Traiffort, Martial Ruat. Distribution of Smoothened at hippocampal mossy fiber synapses.. NeuroReport, 2007, 18 (4), pp.395-9. ⟨10.1097/WNR.0b013e32801421ce⟩. ⟨hal-00142333⟩

Accès au bibtex

2006

ref_biblio

Albane Kessler, Hélène Faure, Christophe Petrel, D. Rognan, M. Cesario, et al.. N1-Benzoyl-N2-[1-(1-naphthyl)ethyl]-trans-1,2-diaminocyclohexanes: Development of 4-chlorophenylcarboxamide (calhex 231) as a new calcium sensing receptor ligand demonstrating potent calcilytic activity.. Journal of Medicinal Chemistry, 2006, 49 (17), pp.5119-28. ⟨10.1021/jm051233+⟩. ⟨hal-00091553⟩

Accès au bibtex

ref_biblio

Karine Loulier, Martial Ruat, Elisabeth Traiffort. Increase of proliferating oligodendroglial progenitors in the adult mouse brain upon Sonic hedgehog delivery in the lateral ventricle. Journal of Neurochemistry, 2006, 98(2), pp.530-542. ⟨10.1111/j.1471-4159.2006.03896.x⟩. ⟨hal-00092638⟩

Accès au bibtex

ref_biblio

Maria Carmen Martinez, Frederic Larbret, Fatiha Zobairi, Josee Coulombe, Najet Debili, et al.. Transfer of differentiation signal by membrane microvesicles harboring hedgehog morphogens.. Blood, 2006, 108 (9), pp.3012-20. ⟨10.1182/blood-2006-04-019109⟩. ⟨hal-00105638⟩

Accès au bibtex

ref_biblio

Christelle Masdeu, Hélène Faure, Josée Coulombe, Angèle Schoenfelder, André Mann, et al.. Identification and characterization of Hedgehog modulator properties after functional coupling of Smoothened to G15.. Biochemical and Biophysical Research Communications, 2006, 349 (2), pp.471-9. ⟨10.1016/j.bbrc.2006.07.216⟩. ⟨hal-00105551⟩

Accès au bibtex

2005

ref_biblio

Karine Loulier, Martial Ruat, Elisabeth Traiffort. Analysis of hedgehog interacting protein in the brain and its expression in nitric oxide synthase-positive cells.. NeuroReport, 2005, 16 (17), pp.1959-62. ⟨hal-00021866⟩

Accès au bibtex

ref_biblio

Olivier Pascual, Elisabeth Traiffort, Darren P. Baker, Alphonse Galdes, Martial Ruat, et al.. Sonic hedgehog signalling in neurons of adult ventrolateral nucleus tractus solitarius.. European Journal of Neuroscience, 2005, 22, pp.389. ⟨10.1111/j.1460-9568.2005.04223.x⟩. ⟨hal-00018205⟩

Accès au bibtex

ref_biblio

Kausik Ray, Justin Tisdale, Robert H. Dodd, Philippe Dauban, Martial Ruat, et al.. Calindol, a positive allosteric modulator of the human Ca(2+) receptor, activates an extracellular ligand-binding domain-deleted rhodopsin-like seven-transmembrane structure in the absence of Ca(2+).. Journal of Biological Chemistry, 2005, 280 (44), pp.37013-20. ⟨10.1074/jbc.M506681200⟩. ⟨hal-00021965⟩

Accès au bibtex

ref_biblio

Caroline Silve, Christophe Petrel, Christine Leroy, Henri Bruel, Eric Mallet, et al.. Delineating a Ca2+ binding pocket within the venus flytrap module of the human calcium-sensing receptor.. Journal of Biological Chemistry, 2005, 280 (45), pp.37917-23. ⟨10.1074/jbc.M506263200⟩. ⟨hal-00022004⟩

Accès au bibtex

ref_biblio

Elisabeth Traiffort, Martial Ruat, Seana O'Regan, François-Marie Meunier. Molecular characterization of the family of choline transporter-like proteins and their splice variants.. Journal of Neurochemistry, 2005, 92 (5), pp.1116-25. ⟨10.1111/j.1471-4159.2004.02962.x⟩. ⟨hal-00086040⟩

Accès au bibtex

ref_biblio

Arthur H. Weston, Mais Absi, Donald T. Ward, Jacqueline Ohanian, Robert H. Dodd, et al.. Evidence in favor of a calcium-sensing receptor in arterial endothelial cells: studies with calindol and Calhex 231.. Circulation Research, 2005, 97 (4), pp.391-8. ⟨10.1161/01.RES.0000178787.59594.a0⟩. ⟨hal-00098392⟩

Accès au bibtex

2004

ref_biblio

Josée Coulombe, Elisabeth Traiffort, Karine Loulier, Hélène Faure, Martial Ruat. Hedgehog interacting protein in the mature brain: membrane-associated and soluble forms.. Molecular and Cellular Neuroscience, 2004, 25 (2), pp.323-33. ⟨10.1016/j.mcn.2003.10.024⟩. ⟨hal-00169750⟩

Accès au bibtex

ref_biblio

Josée Coulombe, Hélène Faure, Bruno Robin, Martial Ruat. In vitro effects of strontium ranelate on the extracellular calcium-sensing receptor.. Biochemical and Biophysical Research Communications, 2004, 323 (4), pp.1184-90. ⟨10.1016/j.bbrc.2004.08.209⟩. ⟨hal-00169742⟩

Accès au bibtex

ref_biblio

Sophie Couvé-Privat, Marc Le Bret, Elisabeth Traiffort, Sophie Queille, Josée Coulombe, et al.. Functional analysis of novel sonic hedgehog gene mutations identified in basal cell carcinomas from xeroderma pigmentosum patients.. Cancer Research, 2004, 64 (10), pp.3559-65. ⟨10.1158/0008-5472.CAN-03-4040⟩. ⟨hal-00136585⟩

Accès au bibtex

ref_biblio

Albane Kessler, Hélène Faure, Christophe Petrel, Martial Ruat, Philippe Dauban, et al.. N2-benzyl-N1-(1-(1-naphthyl)ethyl)-3-phenylpropane-1,2-diamines and conformationally restrained indole analogues: development of calindol as a new calcimimetic acting at the calcium sensing receptor.. Bioorganic and Medicinal Chemistry Letters, 2004, 14 (12), pp.3345-9. ⟨10.1016/j.bmcl.2004.03.056⟩. ⟨hal-00136558⟩

Accès au bibtex

ref_biblio

Albane Kessler, Hélène Faure, Marie Cécile Roussanne, Sandrine Ferry, Martial Ruat, et al.. N(1)-Arylsulfonyl-N(2)-(1-(1-naphthyl)ethyl)-1,2-diaminocyclohexanes: a new class of calcilytic agents acting at the calcium-sensing receptor.. ChemBioChem, 2004, 5 (8), pp.1131-6. ⟨10.1002/cbic.200400049⟩. ⟨hal-00169777⟩

Accès au bibtex

ref_biblio

Christophe Petrel, Albane Kessler, Philippe Dauban, Robert H. Dodd, Didier Rognan, et al.. Positive and negative allosteric modulators of the Ca2+-sensing receptor interact within overlapping but not identical binding sites in the transmembrane domain.. Journal of Biological Chemistry, 2004, 279 (18), pp.18990-7. ⟨10.1074/jbc.M400724200⟩. ⟨hal-00169809⟩

Accès au bibtex

ref_biblio

Martial Ruat, Christophe Petrel. Comment moduler l'activité du récepteur aux ions calcium extracellulaires? [New insights into the pharmacology of the extracellular calcium sensing receptor]. Médecine/Sciences, 2004, 20 (11), pp.980-985. ⟨hal-00169847⟩

Accès au bibtex

ref_biblio

Elisabeth Traiffort, Christèle Dubourg, Hélène Faure, Didier Rognan, Sylvie Odent, et al.. Functional characterization of sonic hedgehog mutations associated with holoprosencephaly.. Journal of Biological Chemistry, 2004, 279 (41), pp.42889-97. ⟨10.1074/jbc.M405161200⟩. ⟨hal-00169857⟩

Accès au bibtex

2003

ref_biblio

Christophe Petrel, Albane Kessler, Fouzia Maslah, Philippe Dauban, Robert H. Dodd, et al.. Modeling and mutagenesis of the binding site of Calhex 231, a novel negative allosteric modulator of the extracellular Ca(2+)-sensing receptor.. Journal of Biological Chemistry, 2003, 278 (49), pp.49487-94. ⟨10.1074/jbc.M308010200⟩. ⟨hal-00172993⟩

Accès au bibtex

ref_biblio

Martial Ruat. Pharmacologie du récepteur aux ions calcium extracellulaires. [Pharmacology of the extracellular calcium ion receptor]. Thérapie, 2003, 58 (5), pp.395-401. ⟨hal-00173003⟩

Accès au bibtex

2002

ref_biblio

Dorota Charytoniuk, Elisabeth Traiffort, P. Hantraye, Jean-Michel Hermel, Alphonse Galdes, et al.. Intrastriatal sonic hedgehog injection increases Patched transcript levels in the adult rat subventricular zone.. European Journal of Neuroscience, 2002, 16 (12), pp.2351-7. ⟨10.1046/j.1460-9568.2002.02412.x⟩. ⟨hal-00173057⟩

Accès au bibtex

ref_biblio

Dorota Charytoniuk, Betina Porcel, José Rodríguez Gomez, Hélène Faure, Martial Ruat, et al.. Sonic Hedgehog signalling in the developing and adult brain.. Journal of Physiology - Paris, 2002, 96 (1-2), pp.9-16. ⟨10.1016/S0928-4257(01)00075-4⟩. ⟨hal-00173029⟩

Accès au bibtex

ref_biblio

Nicole Salès, Raymonde Hässig, Katia Rodolfo, Luigi Di Giamberardino, Elisabeth Traiffort, et al.. Developmental expression of the cellular prion protein in elongating axons.. European Journal of Neuroscience, 2002, 15 (7), pp.1163-77. ⟨10.1046/j.1460-9568.2002.01953.x⟩. ⟨hal-00173163⟩

Accès au bibtex

2001

ref_biblio

Elisabeth Traiffort, Kenneth L. Moya, Hélène Faure, Raymonde Hässig, Martial Ruat. High expression and anterograde axonal transport of aminoterminal sonic hedgehog in the adult hamster brain.. European Journal of Neuroscience, 2001, 14 (5), pp.839-850. ⟨10.1046/j.0953-816x.2001.01708.x⟩. ⟨hal-00173175⟩

Accès au bibtex

2000

ref_biblio

Dorota Charytoniuk, Elisabeth Traiffort, E. Pinard, O. Issertial, J. Seylaz, et al.. Distribution of bone morphogenetic protein and bone morphogenetic protein receptor transcripts in the rodent nervous system and up-regulation of bone morphogenetic protein receptor type II in hippocampal dentate gyrus in a rat model of global cerebral ischemia.. Neuroscience, 2000, 100 (1), pp.33-43. ⟨10.1016/S0306-4522(00)00246-3⟩. ⟨hal-00173296⟩

Accès au bibtex

ref_biblio

Philippe Dauban, Sandrine Ferry, Hélène Faure, Martial Ruat, Robert H. Dodd. N1-Arylsulfonyl-N2-(1-aryl)ethyl-3-phenylpropane-1,2-diamines as novel calcimimetics acting on the calcium sensing receptor.. Bioorganic and Medicinal Chemistry Letters, 2000, 10 (17), pp.2001-4. ⟨10.1016/S0960-894X(00)00382-6⟩. ⟨hal-00173305⟩

Accès au bibtex

ref_biblio

Sandrine Ferry, Elisabeth Traiffort, Jacques Stinnakre, Martial Ruat. Developmental and adult expression of rat calcium-sensing receptor transcripts in neurons and oligodendrocytes.. European Journal of Neuroscience, 2000, 12 (3), pp.872-84. ⟨10.1046/j.1460-9568.2000.00980.x⟩. ⟨hal-00173313⟩

Accès au bibtex

ref_biblio

Françoise Le Bouffant, Pascale Le Minter, Elisabeth Traiffort, Martial Ruat, Fritz Sladeczek. Multiple subcellular localizations of PCTAIRE-1 in brain.. Molecular and Cellular Neuroscience, 2000, 16 (4), pp.388-95. ⟨10.1006/mcne.2000.0881⟩. ⟨hal-00173334⟩

Accès au bibtex

ref_biblio

Seana O'Regan, Elisabeth Traiffort, Martial Ruat, Nathalie Cha, Désiré Compaore, et al.. An electric lobe suppressor for a yeast choline transport mutation belongs to a new family of transporter-like proteins.. Proceedings of the National Academy of Sciences of the United States of America, 2000, 97 (4), pp.1835-40. ⟨10.1073/pnas.030339697⟩. ⟨hal-00172810⟩

Accès au bibtex

1999

ref_biblio

Elisabeth Traiffort, Dorota Charytoniuk, Laurent Watroba, Hélène Faure, Nicole Sales, et al.. Discrete localizations of hedgehog signalling components in the developing and adult rat nervous system.. European Journal of Neuroscience, 1999, 11 (9), pp.3199-214. ⟨10.1046/j.1460-9568.1999.00777.x⟩. ⟨hal-00173344⟩

Accès au bibtex

1998

ref_biblio

B. Grimaldi, Alexandre Bonnin, Marie-Paule Fillion, Martial Ruat, Elisabeth Traiffort, et al.. Characterization of 5-ht6 receptor and expression of 5-ht6 mRNA in the rat brain during ontogenetic development. Naunyn-Schmiedeberg's Archives of Pharmacology, 1998, 357 (4), pp.393-400. ⟨10.1007/pl00005184⟩. ⟨hal-03533908⟩

Accès au bibtex

ref_biblio

James Munis, Joseph Steiner, Martial Ruat, Solomon Snyder. Diamine Oxidase Induces Neurite Outgrowth in Chick Dorsal Root Ganglia by a Nonenzymatic Mechanism. Journal of Neurochemistry, 1998, 70 (3), pp.1323-1326. ⟨10.1046/j.1471-4159.1998.70031323.x⟩. ⟨hal-03533940⟩

Accès au bibtex

ref_biblio

Elisabeth Traiffort, Dorota Charytoniuk, Hélène Faure, Martial Ruat. Regional distribution of Sonic Hedgehog, patched, and smoothened mRNA in the adult rat brain.. Journal of Neurochemistry, 1998, 70 (3), pp.1327-30. ⟨10.1046/j.1471-4159.1998.70031327.x⟩. ⟨hal-00173354⟩

Accès au bibtex

ref_biblio

Loren Walensky, Martial Ruat, Robert Bakin, Seth Blackshaw, Gabriele Ronnett, et al.. Two Novel Odorant Receptor Families Expressed in Spermatids Undergo 5′-Splicing. Journal of Biological Chemistry, 1998, 273 (16), pp.9378-9387. ⟨10.1074/jbc.273.16.9378⟩. ⟨hal-03533874⟩

Accès au bibtex

1997

ref_biblio

Sandrine Ferry, Bruno Chatel, Robert Dodd, Christine Lair, Danielle Gully, et al.. Effects of Divalent Cations and of a Calcimimetic on Adrenocorticotropic Hormone Release in Pituitary Tumor Cells. Biochemical and Biophysical Research Communications, 1997, 238 (3), pp.866-873. ⟨10.1006/bbrc.1997.7401⟩. ⟨hal-03533957⟩

Accès au bibtex

ref_biblio

Magali Mailland, Rudolf Waelchli, Martial Ruat, Hendrikus Boddeke, Klaus Seuwen. Stimulation of Cell Proliferation by Calcium and a Calcimimetic Compound. Endocrinology, 1997, 138 (9), pp.3601-3605. ⟨10.1210/endo.138.9.5417⟩. ⟨hal-03534004⟩

Accès au bibtex

ref_biblio

M.L. Vizuete, Elisabeth Traiffort, M.L. Bouthenet, Martial Ruat, E. Souil, et al.. Detailed mapping of the histamine H2 receptor and its gene transcripts in guinea-pig brain. Neuroscience, 1997, 80 (2), pp.321-343. ⟨10.1016/s0306-4522(97)00010-9⟩. ⟨hal-03533992⟩

Accès au bibtex

Chapitre d'ouvrage

2015

ref_biblio

Lucile Hoch, Martial Ruat. Smoothened Inhibitors in Cancer. Martial Ruat. The Smoothened Receptor in Cancer and Regenerative Medicine, 16, Springer International Publishing, pp 1-11, 2015, Topics in Medicinal Chemistry, 978-3-319-19754-8. ⟨10.1007/7355_2015_85⟩. ⟨hal-01307962⟩

Accès au bibtex

ref_biblio

Martial Ruat, Hélène Faure, Mathieu Daynac. Smoothened, Stem Cell Maintenance and Brain Diseases. Martial Ruat. The Smoothened Receptor in Cancer and Regenerative Medicine, 16, Springer International Publishing, pp 147-171, 2015, Topics in Medicinal Chemistry, 978-3-319-19754-8. ⟨10.1007/7355_2014_83⟩. ⟨hal-01307958⟩

Accès au bibtex

Ouvrages

2015

ref_biblio

Martial Ruat. The Smoothened Receptor in Cancer and Regenerative Medicine. Martial Ruat. Springer International Publishing, 16, 2015, Topics in Medicinal Chemistry (TMC), 978-3-319-19754-8. ⟨10.1007/978-3-319-19755-5⟩. ⟨hal-02498006⟩

Accès au bibtex